CROs
Predictable Enrollment. Confident Delivery.
Polus Health strengthens CRO trial performance with uniform, pre-validated patient pipelines—reducing screen failures, improving forecast accuracy, and helping you deliver timelines sponsors can trust.
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30-Minute Call
Book a time to discuss your current studies, enrollment risk, and whether a Polus-supported pilot is appropriate.

The Reality CROs Face.
- Feasibility ≠ enrollment. What works on paper breaks at site level.
- Variance across sites destroys timelines. Even strong sites stall when prescreening is inconsistent.
- Diversity metrics are under scrutiny. In retina trials especially, representation gaps threaten compliance.
- Rescue sites eat margins. Extensions cost 20–40% more and erode profitability.
- Sponsors blame CROs for delays, regardless of root cause.
You’re managing risk every day. Polus makes recruitment one variable you can finally control.
Why CROs Are Choosing Polus.
You own the enrollment number. You own the timeline. You own sponsor satisfaction.
But site performance varies wildly, feasibility projections often crumble in execution, and screen-fail rates derail even the best-planned timelines.
Polus brings uniformity, predictability, and accuracy to the front-end funnel, so your team can deliver what you promise in bid defense.
See If Polus Can De-Risk Your Enrollment
Start a pilot at 2–3 sites and compare screen-failure rates, randomizations, and timeline accuracy within 60 days.
Polus operates upstream of enrollment to reduce preventable risk, without changing site workflows or disrupting existing delivery models.

How Polus Helps You Protect Your Timelines.
Step 1: Standardize the Front-End Funnel
CROs struggle because site prescreening varies site to site. Polus applies a protocol-specific logic tree, AI models, and human review to standardize prescreening quality across every participating site.
Result: Feasibility projections finally match execution.
Step 2: Deliver High-Probability Candidates Only
Our AI + retinal specialists reduce screen-fails by up to 40%, improving cost-per-randomized patient and eliminating false starts.
We eliminate the noise that forces sites into rescue-mode and CROs into crisis management.
Result: Sponsors see cleaner enrollment curves and fewer delays.
Step 3: Provide Auditable Referral Files
Polus delivers standardized Excel reports containing:
- Verified patient eligibility
- Protocol logic pathways
- Documentation ready for audit
- Flags for diversity targets
- Visit-ready patient referrals
Everything is HIPAA/BAA compliant, IRB-approved, and traceable—ideal for QA and sponsor oversight.
Result: CROs get predictable enrollment inputs they can defend in audits and governance meetings.
Built By Retina Research Professionals
Polus Health was built by clinical research professionals who understand the pressure CROs face to deliver predictable timelines across diverse sites.
We work upstream of enrollment to validate eligibility, imaging, and prescreening inputs before they introduce downstream risk. The result is cleaner handoffs to sites, fewer surprises for sponsors, and greater confidence in delivery.
Polus operates as a neutral layer between sponsors and sites, strengthening execution without disrupting established workflows.

The Polus Guarantee.
Polus Health is built to align with your delivery goals, not add cost or complexity.
- No subscription fees
- No monthly minimums
- One-time admin startup fee
- Only billed for successful patient screenings / enrollments
It’s a simple, transparent model built on trust, results, and shared success. We only succeed when you do.
What You Gain With Polus Health.
Enrollment Insurance
Lower screen-fail rates = more predictable LPI/LPO timelines. CROs using Polus cut cost-per-randomized patient by 15–25%.
Stronger Bid Defenses
Only Polus gives CROs a recruitment differentiator – uniform prescreening, diversity-ready pipelines, and guaranteed SFR improvement.
Fewer Rescue Sites
Better prescreening accuracy reduces the need for mid-study expansions, protecting margins and operational budgets.
Repeating Sponsor Business
Sponsors stay with CROs that deliver. By improving SFR and timeline reliability, Polus helps CROs lock in long-term relationships.
Diversity Metrics Built In
Traceable patient screening and demographic data support FDA/EMA expectations.
CROs can deliver compliance with confidence.
See What You Can Gain
Why Polus Works for CROs.
Polus is your front-end enrollment engine—a workflow layer that standardizes pre-screening across every site so your study runs on schedule.
Predictable enrollment = predictable timelines. Polus is your enrollment insurance policy.

Ready to De-risk Your Enrollment?
Start a Polus-supported pilot at 2–3 sites and compare SFR, randomizations, and timeline accuracy within 60 days.
Request Pilot Details
Share a few details and receive an overview of the Polus-supported pilot.
Schedule a 30-Minute Call
Meet with our team to see whether a Polus-supported pilot is a fit for your current studies.
