CROs

Predictable Enrollment. Confident Delivery.

Polus Health strengthens CRO trial performance with uniform, pre-validated patient pipelines—reducing screen failures, improving forecast accuracy, and helping you deliver timelines sponsors can trust.

The Reality CROs Face.

  • Feasibility ≠ enrollment. What works on paper breaks at site level.
  • Variance across sites destroys timelines. Even strong sites stall when prescreening is inconsistent.
  • Diversity metrics are under scrutiny. In retina trials especially, representation gaps threaten compliance.
  • Rescue sites eat margins. Extensions cost 20–40% more and erode profitability.
  • Sponsors blame CROs for delays, regardless of root cause.

You’re managing risk every day. Polus makes recruitment one variable you can finally control.

Why CROs Are Choosing Polus Health.

You own the enrollment number. You own the timeline. You own sponsor satisfaction.

But site performance varies wildly, feasibility projections often crumble in execution, and screen-fail rates derail even the best-planned timelines.

Polus brings uniformity, predictability, and accuracy to the front-end funnel—so your team can deliver what you promise in bid defense.

How Polus Helps CROs Protect Timelines.

Step 1: Standardize the Front-End Funnel

CROs struggle because site prescreening varies site to site. Polus applies a protocol-specific logic tree, AI models, and human review to standardize prescreening quality across every participating site.

Result: Feasibility projections finally match execution.

Step 2: Deliver High-Probability Candidates Only

Our AI + retinal specialists reduce screen-fails by up to 40%, improving cost-per-randomized patient and eliminating false starts.

We eliminate the noise that forces sites into rescue-mode and CROs into crisis management.

Result: Sponsors see cleaner enrollment curves and fewer delays.

Step 3: Provide Auditable Referral Files

Polus delivers standardized Excel reports containing:

  • Verified patient eligibility
  • Protocol logic pathways
  • Documentation ready for audit
  • Flags for diversity targets
  • Visit-ready patient referrals

Everything is HIPAA/BAA compliant, IRB-approved, and traceable—ideal for QA and sponsor oversight.

Result: CROs get predictable enrollment inputs they can defend in audits and governance meetings.

What CROs Gain with Polus Health.

Enrollment Insurance

Lower screen-fail rates = more predictable LPI/LPO timelines. CROs using Polus cut cost-per-randomized patient by 15–25%.

Stronger Bid Defenses

Only Polus gives CROs a recruitment differentiator—uniform prescreening, diversity-ready pipelines, and guaranteed SFR improvement.

Fewer Rescue Sites

Better prescreening accuracy reduces the need for mid-study expansions, protecting margins and operational budgets.

Repeating Sponsor Business

Sponsors stay with CROs that deliver. By improving SFR and timeline reliability, Polus helps CROs lock in long-term relationships.

Diversity Metrics Built In

Traceable patient screening and demographic data support FDA/EMA expectations.
CROs can deliver compliance with confidence.

Why Polus Works for CROs.

Polus is your front-end enrollment engine—a workflow layer that standardizes pre-screening across every site so your study runs on schedule.

Predictable enrollment = predictable timelines. Polus is your enrollment insurance policy.

Ready to De-risk Your Enrollment?

Start a Polus-supported pilot at 2–3 sites and compare SFR, randomizations, and timeline accuracy within 60 days.

Fill out the and one of our experts will follow up with you in 1-2 business days.